HPE and NVIDIA unveil enhanced AI computing portfolio

Hewlett Packard Enterprise

By Dylan Bushell-Embling
Wednesday, 29 October, 2025

HPE and NVIDIA unveil enhanced AI computing portfolio

HPE has unveiled an expanded NVIDIA AI Computing by HPE product portfolio, aimed at helping make AI easier to deploy at scale by governments, regulated industries and enterprises.

The expanded range includes the second generation of HPE Private Cloud AI, which now includes the new ProLiant Compute DL380a Gen12 servers and NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs.

The latest release promises to offer air-gapped management to enable network-isolated cloud environments for secure, compliant deployments. Meanwhile, HPE Services is offering a solution that uses HPE Private Cloud AI and NVIDIA NeMo to create digital avatar assistants that provide enhanced customer interactions and business support tailored to specific industries.

HPE has also announced additional offerings in the NVIDIA AI Computing by HPE portfolio. The PE ProLiant Compute XD685 now supports eight NVIDIA Blackwell Ultra (B300 GPUs) in a 5U, direct-liquid-cooled HGX chassis.

The HPE ProLiant Compute DL380 Gen12 Server Premier Solution for Azure Local is meanwhile designed to provide secure hybrid cloud infrastructure for running Microsoft Azure services anywhere, while eight HPE ProLiant platforms have been upgraded with augmented AI and graphics performance for organisations in research, education, health care, finance, media, manufacturing and retail.

HPE CTO and EVP and GM for Hybrid Cloud Fidelma Russo said to accelerate widespread AI adoption in enterprises, technology must directly address the core challenges that organisations face around complex deployments and fragmented, highly sensitive data.

“Together with NVIDIA, we offer a different approach with full-stack, private AI factories that simplify operations and help enterprises and governments scale quickly while staying compliant,” she said.

Image credit: iStock.com/gorodenkoff

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